Wheat is the most widely grown crop in the world and has the highest grain production. Most of the grain is used for human consumption, hence it is a staple crop for human well-being. However despite its economic significance, very little is known about the genes that control wheat yield and adaptation. In general, variation for these traits is described mathematically, but not genetically. The ability to identify genes controlling yield and adaptation would greatly enhance wheat breeders' ability to manipulate these genes to improve the crop. The genetic information would also foster the development of better breeding strategies. The purpose of this grant is to couple advanced chromosomal manipulations with extensive field evaluation to identify the chromosomal segments containing genes that control yield and adaptation in hard red winter wheat (the predominant wheat grown in the United States). Specifically a set of lines containing segments of chromosomes that were previously identified as having important effects on yield and traits associated with yield will be developed. These lines containing chromosome segments will be evaluated in replicated field trials in multiple locations in Nebraska. By evaluating these lines, it should be possible to develop an understanding of how many genes on the chromosome affect yield and adaptation, how the genes interact (epistasis or heterosis), and how traits are affected by the genes (pleiotropy or linkage effects). This genetic information and the developed chromosome segment lines will be shared with interested plant breeders, geneticists, and molecular biologist for future research.